Prof. Brunschweiger

• Award "Forum Junge Spitzenforscher, zur Förderung des Transfers innovativer Ideen zum Thema Transformation", Dortmund, 2020, donated by the Foundation Industrieforschung
   
• Innovationspreis in Medizinisch/Pharmazeutischer Chemie, 2019, awarded by the "Fachgruppe Medizinische Chemie der GDCh" and the "Fachgruppe Pharmazeutische/ Medizinische Chemie der DPhG", Würzburg, 2019
   
• BioMedizin-Förderpreis des Vereins zur Förderung der biomedizinischen und klinischen Forschung e.V., Dortmund, 2017
   
• Member of the “Global Young Faculty”, Mercator Research Center Ruhr (MERCUR), 2015.
   
• Neuroallianz Publication Award (silver) 2014 for ChemMedChem 2014, 9, 1704–1724
   
• Poster award for “Uracil nucleotide mimetics as NTPDase2 inhibitors”, 8th International Symposium on ‘Adenosine and Adenine Nucleotides’; Ferrara, 2006

• PhD prize for Dr. Verena Kunig, FiMC (online), 2022
   
• Poster prize for Dr. Suzanne Willems, FiMC (online), 2022
   
• Poster prizes for Dr. Marco Potowski and Verena Kunig, FiMC (online), 2021
   
• Poster prize for Verena Kunig, EFMC conference (online), 2020
   
• Poster prize for Verena Kunig, 7th Int. conference on MCR Chemistry, Düsseldorf, 2019
   
• Klaus-Grohe award for Dr. Mateja Klika Škopić, FiMC Jena, 2018
   
• Nüsslein-Volhard scholarship for Mateja Klika Škopić to support mothers who pursue a scientific career, 2016

• Frontiers in Medicinal Chemistry, March 2021 (online seminar)
   
• Advances in Chemical Biology, January 2021 (online seminar)
   
• Biochemistry, Münster, March 2020 (postponed due to coronavirus pandemia)
   
• Chemiedozententagung, Dresden, March/April 2020 (cancelled due to coronavirus pandemia)
   
• Bioheterocycles, Ghent, Belgium, June 2019
   
• Leibniz Conference on Bioactive Compounds, Dresden, Germany, April 2019
   
• Chemiedozententagung, Koblenz, April 2019
   
• Advances in Chemical Biology, Frankfurt, Germany, January 2019
   
• Jahrestagung der Deutschen Pharmazeutischen Gesellschaft, Hamburg, Germany, September 2018
   
• 7th EuCheMS Chemistry Congress, Liverpool, UK, August, 2018
   
• International Helmholtz Drug Discovery Conference, Munich, Germany, April 2018
   
• Leibniz Conference on Bioactive Compounds, Halle, Germany, April 2018
   
• Advances in Chemical Biology, Frankfurt, Germany, January 2018
   
• Jahrestagung der Deutschen Pharmazeutischen Gesellschaft, Saarbrücken, Germany, September 2017
   
• Molecular Basis of Life, conference organized by the German Society for Biochemistry and Molecular Biology, Bochum, Germany, September 2017
   
• VIII. Nucleinsäurechemie-Treffen, Mainz, Germany, September 2017
   
• 26th International Society of Heterocyclic Chemistry Congress, Regensburg, Germany, September 2017
   
• 7th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC’17), Vienna, Austria, August 2017
   
• The Fourth International Scientific Conference “Advances in Synthesis and Complexing”, Moscow, Russia, April 2017
   
• First German-Russian Interdisciplinary Student Workshop "Nanoscale Interdisciplinary Research: Physics, Chemistry, Biology, Mathematics", Moscow, Russia, April, 2017
   
• Leibniz Conference on Bioactive Compounds, Freising, Germany, March 2017
   
• Chemiedozententagung, Marburg, March 2017
   
• International Conference “Modern Trends in Organic Chemistry”, Dombay, Russia, June 2016
   
• Gemeinsames Symposium der Max-Planck-Gesellschaft und RIKEN, Berlin, Germany, April 2016

• XXVII EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC) 2022, session head and invited talk
   
• Elsevier/Reaxys, October 2021 (online seminar on KNIME for chemistry data analysis)
   
• Drug Discovery UK, October 2021 (online seminar)
   
• ACS National Meeting, March 2021 (online seminar)
   
• Reaxys/Elsevier, February 2021 (online presentation in a user community meeting on our use of KNIME for chemistry database search)
   
• eMolecules, November 2020 (online seminar)
   
• Global Medicinal Chemistry Summit, November 2020 (online seminar)
   
• Elsevier/Reaxys, October 2020 (online seminar)
   
• AstraZeneca, September 2020 (online seminar)
   
• Sanofi, May 2020 (online)
   
• ACS National Meeting, San Francisco, USA, August 2020 (online due to coronavirus pandemia)
   
• Pacifichem, Honolulu, USA, December 2020 (postponed to 2021, online)
   
• ACS National Meeting, Philadelphia, USA, March 2020 (postponed due to coronavirus pandemia)
   
• Global Medicinal Chemistry & Protein Degradation Summit, London, UK, October 2019
   
• EFMC-YMCS congress, Athens, Greece, September 2019
   
• Frontiers in Medicinal Chemistry, Berne, Switzerland, February 2017
   
• Frontiers in Medicinal Chemistry, Würzburg, Germany, March 2019
   
• Jungchemikerforum, Bochum, June 2018
   
• Global Medicinal Chemistry & GPCR Leaders Summit, London, UK, November 2017
   
• GTCBio European Pharma Summit, Berlin, Germany, November 2017
   
• 7th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC’17), Vienna, Austria, August 2017
   
• ACS National Meeting, Washington DC, USA, August 2017
   
• Cancer Research UK, London, UK, November 2017
   
• Bayer AG, Wuppertal, Germany, March 2017
   
• Novartis Pharma AG, Basel, Switzerland, March 2016

• Prof. Alexander Dömling (U. Groningen): encoded Ugi reaction^* and MDM2 inhibitor design^*
   
• Prof. Mike Waring (U. Newcastle): DNA-encoded Suzuki reactions,^* academic DEL resource
   
• Dr. Sam Butterworth (U. Manchester):  academic DEL resource
   
• Prof. Ralf Weberskirch (TU Dortmund): nanoheterogeneous reaction systems for DEL synthesis^*
   
• Prof. Roland Fried (TU Dortmund): computer-assisted workflows for sequencing data analysis^*
   
• Prof. Norbert Kockmann (TU Dortmund): laboratory automation for DEL synthesis,^* microreactors  
   
• Prof. Stefan Kast (TU Dortmund): ligand/structure-based design of TEAD-YAP inhibitors
   
• Dr. Christiane Ehrt (U. Hamburg): computational DEL design and chemical space analysis^*
   
• Dr. Alexander Vakalopoulus (Bayer): DNA-encoded library design^*
   
• Prof. Donat Kögel (U. Frankfurt): DEL design for Bcl proteins and BAG3
   
• Prof. Jeffrey Bode (ETH Zürich): DEL chemistry development^*

collaborations marked with an asterix have led to publications

Reviewer for journals

• Angew. Chem. Int. Ed., J. Am. Chem. Soc., Nat. Chem., Nat. Commun., Org. Lett., ACS Chem. Biol., J. Med. Chem., MedChemComm., Bioconjug. Chem., Curr. Top. Med. Chem., Bioorg. Med. Chem.; ACS Comb. Sci.

Reviewer for third-party funding applications

• Swiss National Fund (repeatedly)
• National Research Council Canada

Editorial Activities

• Guest editor for a Special Issue in Bioorganic and Medicinal Chemistry Letters on “DNA-encoded libraries” published in 2021 (15 contributions from the field).
• Co-editor with Prof. Damian Young (Baylor College of Medicine, Houston, USA) of a book titled “DNA-encoded Chemistry” to be published within the series Topics in Medicinal Chemistry.

Member of scientific committee

• Member of the International Scientific Committee of the XXVII International Symposium on Medicinal Chemistry 2022.

Affiliations

• Gesellschaft Deutscher Chemiker (GDCh)
• Deutsche Nucleinsäurechemiegemeinschaft (DNG)
• Schweizerische Chemische Gesellschaft (SCG)
• Deutsche Pharmazeutische Gesellschaft (DPhG)
• DECHEMA

Institutional activities

• Participation in faculty teaching
• Faculty member of the International Max Planck Research School “Chemical Biology” (since 2013)
• Coordination of the lecture “Medicinal Chemistry II - Case Studies” which is in part given by scientists from the Lead Discovery Center GmbH, Dortmund, and Bayer Pharma AG, Wuppertal (since 2013)
• Organization of excursions for MSc students of Chemical Biology to Bayer Pharma AG, Wuppertal (2014, 2015)
• Member of three commissions to hire faculty (“Berufungskommissionen”)
• Organization of the newly established institute´s colloquium: “Modern Drug Discovery” which has attracted regular attendance beyond the University (since 2013)
• Lectures on drug research for school students, “Schnupper-Uni”, 2013-2015
• Lectures on Medicinal Chemistry and Chemical Biology for chemistry teachers, Chemielehrerfortbildungen, 2014-2016

• UK academic DNA-encoded library screening resource
  funded by the Wellcome Trust, with Prof. Mike Waring (University of Newcastle) and Dr. Sam Butterworth (University Manchester), co-applicant, May 2021 - April 2026.
• Design and Screening of Advanced DNA-Encoded Libraries
  research project with Bayer AG, follow-up to successful delivery of project 6 “Expanding the chemical space of DNA-encoded libraries”, Dec. 2020 - Nov. 2022.

• Entwicklung von Strategien zur Hochdurchsatzsynthese von genetisch kodierten Molekülbibliotheken heterocyclischer Systeme und Anwendung zur Identifizierung von Inhibitoren von Apoptose-Inhibitoren (IAP) als Modellsysteme
  funded by the DFG, Jul. 2020 - Jun. 2023, with Prof. Norbert Kockmann (Faculty of Chemical and Biological Engineering, TU Dortmund).
• Validierung von polymergestützen, mizellaren Reaktoren für die Herstellung von genetisch kodierten Screeningbibliotheken
  EFRE-funded NRW-Patentvalidierung, main applicant: Prof. Weberskirch (TU Dortmund), Jan. 2020 - Dec. 2021.

• Expanding the chemical space of DNA-encoded libraries
  research project with Bayer AG; July 2018 – July 2020.

• Targeting the therapy resistance factors BAG3 und Bcl-xL in solid tumors
  funded by the DFG, collaboration project with Prof. Donat Kögel (University of Frankfurt), and Prof. Stefan Kast (TU Dortmund University); July 2018 – June 2021.

• Funktion des APBB1 in Abhängigkeit seiner subzellulären Lokalisation - Relevanz für Morbus Alzheimer
  funded by Mercator Research Center Ruhr (MERCUR), co-applicant, with Dr. Thorsten Müller, University of Bochum, and Prof. Shirley Knauer, University of Duisburg-Essen; June 2017 – May 2019.

• Click & Code
  research project with Merck KGaA; November 2018 – April 2019.

• Towards chemoresistant genetic information
  funded by Boehringer Ingelheim foundation; December 2017 – November 2018.