Solid microemulsion preconcentrates on pH responsive metal-organic framework for tableting
04/13/2023Congratulations to Lena Scheller & team. She developed a powder-form microemulsion adsorbed to a metalloorganic framework (MOF). Once the powder reaches the stomach, the MOF disintegrates, releasing the adsorbed molecules that readily form a microemulsion. The concept might be an interesting oral delivery form for poorly water-soluble drugs. A patent is pending, the article has been published in the European Journal of Pharmaceutics and Biopharmaceutics (EJPB).
https://www.sciencedirect.com/science/article/abs/pii/S0939641123000760
“Reprinted from European Journal of Pharmaceutics and Biopharmaceutics, Volume 186, May 2023, Pages 105-111, Scheller L., Bachmann S., et al., ‘Solid microemulsion preconcentrates on pH responsive metal-organic framework for tableting’
Copyright 2023, with kind permission from Elsevier.”
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